- ESPript, 'Easy Sequencing in PostScript', is a program that renders sequence similarity and secondary structure information from aligned sequences for analysis and publication purpose.
- Key features:
- ESPript is a utility, whose output is a PostScript / PDF / PNG or TIFF file of aligned sequences with graphical enhancements.
- Its main input is a file of pre-aligned sequences in Clustal, FASTA, MultAlin, NPS@ or ProDom format.
- The program calculates a similarity score for each residue of the aligned sequences.
- Secondary structure elements can be added to the multiple sequence alignment using PDB, CIF or DSSP files.
- A typical ESPript figure shows:
- aligned sequences,
- similarities,
- consensus,
- accessibility,
- hydropathy,
- secondary structure elements,
- intermolecular contacts,
- user-supplied markers.
- Biotool Web servers interfaced with ESPript:
- ENDscript:
- ENDscript is a friendly Web server that automatically extracts and displays a comprehensive analysis of primary to quaternary protein structure information. Several ENDscript representations are produced with ESPript.
- T-Coffee:
- T-Coffee is a collection of tools for caclulating, evaluating and manipulating multiple alignments of DNA, RNA and protein sequences and structures.
- NPS@:
- NPS@ is an interactive Web server dedicated to protein sequence analysis. NPS@ can perform multiple sequence alignments using ClustalW or MultAlin, and the resulting output can be displayed using ESPript.
- MultAlin:
- MultAlin is a program for multiple sequence alignment with hierarchical clustering. Resulting alignments can be rendered with ESPript.
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